To resolve this issue, select a DSN that is created using a 32-bit ODBC driver in the 32-bit Administrator. A 32-bit ODBC DSN can be created on Windows 64-bit as follows: Go to Start Run. Type the following: C: windows syswow64 odbcad32.exe. Select the ODBC driver from the list. Configure the DSN. DSN contains an architecture mismatch between the Driver and Application- windows 8 nheinze Dec 8, 2014 11:38 AM ( in response to [email protected] ) There's no way around it, with 64-bit Informatica software you have to use a 64-bit ODBC driver.